Antibodiesthat do more.

Metaphore designs antibodies with unique mechanisms of action for new ways to treat disease.

Why it matters

Expanding what’s possible.

Most antibody medicines are designed to block biology to treat disease. But many diseases require a different approach, like activating a pathway, precisely tuning signaling, engaging multiple targets, or combining many actions in one medicine.

Metaphore starts with biology in living systems, using proprietary functional data and AI/ML to design antibodies with new capabilities.

By designing antibodies with unique mechanisms of action, Metaphore is expanding the reach of antibody-based medicines. These medicines also have the potential to deliver better efficacy, greater durability, more practical dosing, and improved tolerability to improve patient outcomes.

New ways to treat disease. More options for patients.

  • Expanded therapeutic reach

    Extend antibody-based medicines into diseases that require more than blocking biology.

  • Greater efficacy and durability

    Build the intended mechanism into each molecule from the start.

  • Simpler dosing

    Use antibody durability to pursue longer intervals between treatments.

  • More precise biological control

    Direct activity with greater precision to improve tolerability.

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